Abstract: In the paper, the reasons for the time shifts of absorption signal and the formation of double peaks for lead in graphite furnace atomizer are described and the atomization of lead to be affected by partial oxygen pressure near the tube wall in graphite furnace is discussed as well. The experiments show that Mg, Ca, Na, Fe and Cu chlorides can cause the depression of absorption signal for lead in varying degrees,and the influence of chloride matrices on lead was mainly in the solid phase and the process of vaporizing sample.