高等学校化学学报

高等学校化学学报 ›› 1989, Vol. 10 ›› Issue (6): 650.

• 研究简报 • 上一篇    下一篇

3,5-环-孕甾-6-甲氧基-20-S-22-醛的立体选择性合成

刘兴平1, 李裕林1, 梁晓天2   

  1. 1. 兰州大学有机化学研究所;
    2. 中国医学科学院药物研究所
  • 收稿日期:1987-11-24 出版日期:1989-06-24 发布日期:1989-06-24
  • 通讯作者: 刘兴平
  • 基金资助:

    国家教育委员会科学基金

Stereoselective Synthesis of3,5-Cyclo-Pregnane-6- Methoxyl-20-S-22-Aldehyde

Liu Xing ping1, Li Yulin1, Liang Xiaolian2   

  1. 1. Institute of Organic Chemistry, Lanzhou University, Lanzhou;
    2. Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing
  • Received:1987-11-24 Online:1989-06-24 Published:1989-06-24

PDF (PC)

摘要： 油菜甾醇内酯(brassinolide)(1)是一种高效植物生长激素,一些实验室曾成功地进行了合成[1.2](这里有图片19890621-650-2.gif)。

关键词: 油莱甾醇内酰, 立体选择性合成, 薯蓣皂甙元, 20-S-22-甾醛

Abstract: The stereoselective synthesis of 3,5-cyclo-pregnane-6-methoxyl-20-S-22-aldehyde(7),which is the key intermediate of the synthesis of brassinolide(1) and its analogous, was carried out with diosgenin as starting material. In this reaction the e,e is 86.2%.

Key words: Brassinolide, Stereoselective synthesis, Diosgenin, 20-S-22-steroidal aldehyde

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