一种基于胆固醇的荧光小分子胶凝剂的合成及其胶凝行为

高等学校化学学报 ›› 2009, Vol. 30 ›› Issue (8): 1651.

一种基于胆固醇的荧光小分子胶凝剂的合成及其胶凝行为

晏妮, 杨美妮, 刘凯强, 房喻

应用表面与胶体化学教育部重点实验室, 陕西师范大学化学与材料科学学院, 西安 710062

收稿日期:2009-03-30 出版日期:2009-08-10 发布日期:2009-08-10
通讯作者: 房喻, 男, 博士, 教授, 博士生导师, 主要从事胶体与界面化学及光物理技术应用研究. E-mail: yfang@snnu.edu.cn
基金资助:
国家自然科学基金(批准号: 20674048, 20773083)资助.

Synthesis and Gelation Behavior of a Fluorescent Active Low-Molecular Mass Organic Gelator Based on Cholesterol

YAN Ni, YANG Mei-Ni, LIU Kai-Qiang, FANG Yu*

Key Laboratory of Applied Surface and Colloid Chemistry of Ministry of Education, School of Chemistry and Materials Science, Shaanxi Normal University, Xi′an 710062, China

Received:2009-03-30 Online:2009-08-10 Published:2009-08-10
Contact: FANG Yu. E-mail: yfang@snnu.edu.cn
Supported by:
国家自然科学基金(批准号: 20674048, 20773083)资助.

摘要/Abstract

摘要：

合成并表征了一种含7-硝基苯并-2-氧杂-1,3-二唑基(7-Nitrobenzo-2-oxa-1,3-diazol-4-yl)的胆固醇衍生物(NBD-C), 考察了其在30种溶剂中的胶凝行为. 实验结果表明, NBD-C对乙腈具有很强的胶凝作用, 且该凝胶体系具有显著的剪切触变性. 对干凝胶的显微分析发现, 在不同溶剂中, NBD-C具有不同的聚集结构. 红外光谱(FTIR)、核磁共振光谱(¹H NMR)和荧光光谱研究结果表明, 除了胆固醇的范德华堆积作用之外, 分子间氢键作用也是该化合物聚集的重要驱动力.

关键词: 超分子凝胶; 荧光胶凝剂; 胆固醇; 剪切触变性

Abstract:

A new 7-nitrobenzo-2-oxa-1,3-diazol-4-yl-appended cholesterol derivative(NBD-C) was synthesized and characterized, and its gelation ability was evaluated in 30 solvents. It was found that NBD-C is an efficient gelator of acetonitrile, and the gel system possesses very smart thixotropic property. Scanning electron microscopy(SEM) observation showed that the gelator aggregated into different supramolecular structures in different solvents. FTIR, ¹H NMR and fluorescence spectroscopy studies revealed that in addition to the van der Waals interaction between the cholesterol units of the gelator molecules, intermolecular hydrogen-bonding also plays crucial rule for the spontaneous formation of the gel networks.

Key words: Supramolecular gel; Fluorescent gelator; Cholesterol; Thixotropic property

TrendMD:

晏妮, 杨美妮, 刘凯强, 房喻. 一种基于胆固醇的荧光小分子胶凝剂的合成及其胶凝行为. 高等学校化学学报, 2009, 30(8): 1651.

YAN Ni, YANG Mei-Ni, LIU Kai-Qiang, FANG Yu*. Synthesis and Gelation Behavior of a Fluorescent Active Low-Molecular Mass Organic Gelator Based on Cholesterol. Chem. J. Chinese Universities, 2009, 30(8): 1651.

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