关键词: 原位聚合; 微流控芯片制备; 玻璃纤维丛; 微混合器

Abstract:

A new method was established for the fabrication of seamless polymer microfluidic chips. By the method, seamless PMMA microfluidic chips were easily fabricated by in situ polymerization of monomer solution casting on a channel mold temporarily fixed with pieces of fine iron wires by a magnet beneath the polymerizing container. Seamless channels were formed by bonding two pieces of 70%—80% polymerized PMMA slides of which one was preprinted with channels. Glass-fibers-embedded microfluidic mixers have also been fabricated in the same way where a section of about 2 mm glass-fiber bundle was inserted between two wires before casting polymerizing solution. With such a mixer, ideal mixing was easily achieved at Re≥22. This method features easy manipulation and low cost, it fits ordinary chemistry laboratories, requiring no clean room or lithographic facilities.

Key words: In situ polymerization fabrication; Microfluidic chip fabrication; Embedment of glass fibers; Micromixer