高等学校化学学报

高等学校化学学报

• 研究论文 • 上一篇    下一篇

云南重楼中的新甾体皂苷

徐暾海1, 毛晓霞2, 徐雅娟2, 解生旭2, 赵洪峰2, 司云珊2, 韩冬2, 李彧1, 牛建昭1, 徐东铭2   

    1. 北京中医药大学中药学院中药化学系, 北京 100102;
    2. 吉林省中医中药研究院中药化学实验室, 长春 130021
  • 收稿日期:2007-05-09 修回日期:1900-01-01 出版日期:2007-12-10 发布日期:2007-12-10
  • 通讯作者: 徐雅娟

New Steroidal Saponin from Paris polyphylla Sm. var. yunnanensis(France.)Hand.-Mazz.

XU Tun-Hai1, MA Xiao-Xia2, XU Ya-Juan2*, XIE Sheng-Xu2, ZHAO Hong-Feng2, SI Yun-Shan2, HAN Dong2, LI Yu1, NIU Jian-Zhao1, XU Dong-Ming2   

    1. Department of Chinese Medicine Chemistry, School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100102, China;
    2. Laboratory of Chinese Medicine Chemistry, Academy of Traditional Chinese Medicine and Material Medica of Jilin Province, Changchun 130021, China
  • Received:2007-05-09 Revised:1900-01-01 Online:2007-12-10 Published:2007-12-10
  • Contact: XU Ya-Juan

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被引次数

20

摘要： 从云南重楼Paris polyphylla Sm. var. yunnanensis(France. )Hand.-Mazz.的干燥根茎中分离鉴定了4个甾体皂苷(1~4), 其中化合物1是新化合物, 采用波谱技术鉴定其结构为24-O-β-D-吡喃半乳糖基-(23S,24S)-螺甾-5, 25(27)-二烯-1β,3β,23,24-四醇-1-O-β-D-吡喃木糖基(1→6)-β-D-吡喃葡萄糖基(1→3)[α-L-吡喃鼠李糖基(1→2)]-β-D-吡喃葡萄糖苷.

关键词: 重楼, 活性成分, 甾体皂苷

Abstract: Traditional Chinese Medicine “zhonglou”(Paris polyphylla) is the important medicine used to treat traumatism. A new steroidal saponin, together with four known steroidal saponins, was isolated from the rhizoma of Paris polyphylla. The structure of the new steroidal saponin, named Paripolyside A was elucidated as 24-O-β-D-galactopylanosyl-(23S,24S)-spirosta-5, 25(27)-diene-1β,3β,23, 24-tetrol-1-O-β-D-xylopylanosyl(1→6)-β-D-glucopyranosyl(1→3)[α-L-rhamnopyranosyl(1→2)]-β-D-glucopyranoside mainly by using 1D, 2D NMR techniques, ESI-MS analysis as well as chemical methods.

Key words: Paris polyphylla, Active composition, Steroidal saponin

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