高等学校化学学报

高等学校化学学报 ›› 2000, Vol. 21 ›› Issue (S1): 90.

• Analytical Sciences • 上一篇    下一篇

Study on the Basic Conformation of Proteins by Electrospray Ionization-Mass Spectrometry (ESI-MS)

GU Sheng1, SHEN Jin-Can1, ZHUANG Zhi-Xia1, WANG Xiao-Ru1, GAO Gui-Ying2   

  1. 1. The Key Laboratory of Analytical Science of Ministry of Education and Department of Chemistry, Xiamen University, Xiamen 361005;
    2. Department of Chemistry, Xiamen University, Xiamen 361005
  • 出版日期:2000-12-31 发布日期:2000-12-31
  • 基金资助:

    Supported by National Foundation of Science of China.

Study on the Basic Conformation of Proteins by Electrospray Ionization-Mass Spectrometry (ESI-MS)

GU Sheng1, SHEN Jin-Can1, ZHUANG Zhi-Xia1, WANG Xiao-Ru1, GAO Gui-Ying2   

  1. 1. The Key Laboratory of Analytical Science of Ministry of Education and Department of Chemistry, Xiamen University, Xiamen 361005;
    2. Department of Chemistry, Xiamen University, Xiamen 361005
  • Online:2000-12-31 Published:2000-12-31
  • Supported by:

    Supported by National Foundation of Science of China.

PDF (PC)

摘要：

Proteins are of great importance in many processes involving natural life, biology and descendiblity. Proteins have been analyzed using various chemical/biological methods. However with those traditional methods, the variety of information related to the conformation of protein complex is very difficult to be obtained The emergence of electrospary ionization-mass spectrometry (ESI-MS) makes it possible to obtain some characteristics information of the protein complexes[1]. Multiple charging is one of the hallmarks of electrospray ionization of macromolecules. The determination of macromolecules mass from the spectrum of multiply charged ions is facilitated by the coherence of charge states[2].

Abstract:

Proteins are of great importance in many processes involving natural life, biology and descendiblity. Proteins have been analyzed using various chemical/biological methods. However with those traditional methods, the variety of information related to the conformation of protein complex is very difficult to be obtained The emergence of electrospary ionization-mass spectrometry (ESI-MS) makes it possible to obtain some characteristics information of the protein complexes[1]. Multiple charging is one of the hallmarks of electrospray ionization of macromolecules. The determination of macromolecules mass from the spectrum of multiply charged ions is facilitated by the coherence of charge states[2].

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