高等学校化学学报

高等学校化学学报 ›› 2000, Vol. 21 ›› Issue (S1): 79.

• Analytical Sciences • 上一篇    下一篇

Determination of Epicholestanol and Coprostanol by Gas Chromatography-Mass Spectrometry

ZHANG Hong1,2, LIANG Xin-Le2, HAN Jian-Zhong2, PAN Yuan-Jiang1   

  1. 1. Department of Chemistry, Zhejiang University, Hangzhou 310027;
    2. Department of Food Science and Engineering, Hangzhou University of Commerce, Hangzhou 310035
  • 出版日期:2000-12-31 发布日期:2000-12-31

Determination of Epicholestanol and Coprostanol by Gas Chromatography-Mass Spectrometry

ZHANG Hong1,2, LIANG Xin-Le2, HAN Jian-Zhong2, PAN Yuan-Jiang1   

  1. 1. Department of Chemistry, Zhejiang University, Hangzhou 310027;
    2. Department of Food Science and Engineering, Hangzhou University of Commerce, Hangzhou 310035
  • Online:2000-12-31 Published:2000-12-31

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摘要：

Coprostanol and epicholestanol are tow kinds of steroids, and have the same constitutions. Coprostanol, 5β-cholestane-3β-ol, it is a sterol formed exclusively in the gut of man and higher mammals, has been recognized as a good indicator of pollution of water resources by sewage discharge. In order to complete resolution of chromatography peak, coprostanol need to be converted into its corresponding trimethylsilyl derivative. Epicholestanol, 5α-cholestane-3α-ol, was used in oral compositions for periodonted disease control.

Abstract:

Coprostanol and epicholestanol are tow kinds of steroids, and have the same constitutions. Coprostanol, 5β-cholestane-3β-ol, it is a sterol formed exclusively in the gut of man and higher mammals, has been recognized as a good indicator of pollution of water resources by sewage discharge. In order to complete resolution of chromatography peak, coprostanol need to be converted into its corresponding trimethylsilyl derivative. Epicholestanol, 5α-cholestane-3α-ol, was used in oral compositions for periodonted disease control.

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