高等学校化学学报 ›› 2000, Vol. 21 ›› Issue (S1): 62.

• Analytical Sciences • 上一篇    下一篇

Study on the Dye-Doped Funcionalized Silica Nanoparticles for The Recognition of SmIgG+B Lymphocytes

WANG Ke-Min, HE Xiao-Xiao, XIAO Dan, LI Jun, YANG Xiao-Hai, LI Qi   

  1. College of chemistry and chemical Engineering, Hunan university, Changsha 410082
  • 出版日期:2000-12-31 发布日期:2000-12-31

Study on the Dye-Doped Funcionalized Silica Nanoparticles for The Recognition of SmIgG+B Lymphocytes

WANG Ke-Min, HE Xiao-Xiao, XIAO Dan, LI Jun, YANG Xiao-Hai, LI Qi   

  1. College of chemistry and chemical Engineering, Hunan university, Changsha 410082
  • Online:2000-12-31 Published:2000-12-31

摘要:

The development of sensitive non-isotopic detection sys tem for biological and medicinal applications, such as single cell analyse, DNA sequence, clinical diagnose etc., has driven nanomaterials more towards cell biology and ultrasensitive immunoassay[1]. Semiconductor nanoparticles have been used for coupling biomolecules but suffer from some disadvantages including poor solubility in water, blinking properties or low quantum yields[1,3,4]. In this paper, we developed a novel dye-doped functionalized silica nanoparticles and used for detection of SmIgG+ B lymphocytes.

Abstract:

The development of sensitive non-isotopic detection sys tem for biological and medicinal applications, such as single cell analyse, DNA sequence, clinical diagnose etc., has driven nanomaterials more towards cell biology and ultrasensitive immunoassay[1]. Semiconductor nanoparticles have been used for coupling biomolecules but suffer from some disadvantages including poor solubility in water, blinking properties or low quantum yields[1,3,4]. In this paper, we developed a novel dye-doped functionalized silica nanoparticles and used for detection of SmIgG+ B lymphocytes.

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