高等学校化学学报

高等学校化学学报 ›› 2000, Vol. 21 ›› Issue (S1): 50.

• Analytical Sciences • 上一篇    下一篇

Simultaneous Determination of Pseudoephedrine, Paracetamol and Dextromethorphan by Capillary Electrophoresis with Diode-array Detection

ZHANG Lan1, CHEN Guo-Nan1, FANG Yu-Zhi2   

  1. 1. Department of Chemistry, Fuzhou University, Fujian, Fuzhou 350002;
    2. Department of Chemistry, East China Normal University, Shanghai 200062
  • 出版日期:2000-12-31 发布日期:2000-12-31

Simultaneous Determination of Pseudoephedrine, Paracetamol and Dextromethorphan by Capillary Electrophoresis with Diode-array Detection

ZHANG Lan1, CHEN Guo-Nan1, FANG Yu-Zhi2   

  1. 1. Department of Chemistry, Fuzhou University, Fujian, Fuzhou 350002;
    2. Department of Chemistry, East China Normal University, Shanghai 200062
  • Online:2000-12-31 Published:2000-12-31

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摘要：

Some analytical methods, such as titration[1], TLC[2], GLC[3], HPLC[4] and spectrophotometry[5] for determination of single ingredient of pseudoephedrine hydrochloride (PSED), paracetamol (PRCT) and dextromethorphan hydrochloride (DEMP) in some mixture have been reported. However, there were no papers for determination of PSED, PRCT and DEMP simultaneously in one tablet. The methods mentioned above needed complex procedures or required some solvents, which might result from pollution, and both of them consumed long time to complete the separation. Therefore it is necessary to develop a new analytical method which could save time and cost.

Abstract:

Some analytical methods, such as titration[1], TLC[2], GLC[3], HPLC[4] and spectrophotometry[5] for determination of single ingredient of pseudoephedrine hydrochloride (PSED), paracetamol (PRCT) and dextromethorphan hydrochloride (DEMP) in some mixture have been reported. However, there were no papers for determination of PSED, PRCT and DEMP simultaneously in one tablet. The methods mentioned above needed complex procedures or required some solvents, which might result from pollution, and both of them consumed long time to complete the separation. Therefore it is necessary to develop a new analytical method which could save time and cost.

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