高等学校化学学报

高等学校化学学报 ›› 2000, Vol. 21 ›› Issue (S1): 458.

• Synthetic Sciences • 上一篇    下一篇

Synthesis of Some New Pyrazolopyrimidines and Pyrazolotriazines

HU Fang-Zhong, ZOU Xiao-Mao, LU Rong-Hua, YANG Hua-Zheng   

  1. State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071
  • 出版日期:2000-12-31 发布日期:2000-12-31
  • 基金资助:

    Project supported by the National Natural Science of Foundation of China (No. 29832050) and Doctors' Special Funds of Ministry of Education.

Synthesis of Some New Pyrazolopyrimidines and Pyrazolotriazines

HU Fang-Zhong, ZOU Xiao-Mao, LU Rong-Hua, YANG Hua-Zheng   

  1. State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071
  • Online:2000-12-31 Published:2000-12-31
  • Supported by:

    Project supported by the National Natural Science of Foundation of China (No. 29832050) and Doctors' Special Funds of Ministry of Education.

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摘要：

In view of the biological activities of 5-aminopyrazoles, e.g. tranquilizing and analgesic properties, some of new fused pyrazolopyrimidines and pyrazolotriazines were synthesized. 5-Amino 3-substituting group 4-cyano (or ethoxycarbonyl) pyrazoles 2 were prepared via the reaction of 1 with hydrazine hydrate in ethanol at room temperature (Scheme 1).

Abstract:

In view of the biological activities of 5-aminopyrazoles, e.g. tranquilizing and analgesic properties, some of new fused pyrazolopyrimidines and pyrazolotriazines were synthesized. 5-Amino 3-substituting group 4-cyano (or ethoxycarbonyl) pyrazoles 2 were prepared via the reaction of 1 with hydrazine hydrate in ethanol at room temperature (Scheme 1).

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