高等学校化学学报

高等学校化学学报 ›› 2000, Vol. 21 ›› Issue (S1): 36.

• Analytical Sciences • 上一篇    下一篇

Determination of Mercury in some TCMs (Traditional Chinese Medicines) by ICP-MS and Sepeciation of Mercury Species Using Ion-Exchange Chromatography

WU Xi-Hong1, GONG Hai-Fang1, CHEN Fa-Rong1, ZHUANG Zhi-Xia1, SUN Da-Hai1, WANG Xiao-Ru1, Frank S. C. LEE2   

  1. 1. The Key Laboratory of Analytical Sciences of the Ministry of Education and Department of Chemistry, Xiamen University, Xiamen, 361005;
    2. Department of Chemistry, Hong Kong Baptist University, Hong Kong
  • 出版日期:2000-12-31 发布日期:2000-12-31
  • 基金资助:

    Supported by the National Natural Science Foundation of China (29875024, 29735160).

Determination of Mercury in some TCMs (Traditional Chinese Medicines) by ICP-MS and Sepeciation of Mercury Species Using Ion-Exchange Chromatography

WU Xi-Hong1, GONG Hai-Fang1, CHEN Fa-Rong1, ZHUANG Zhi-Xia1, SUN Da-Hai1, WANG Xiao-Ru1, Frank S. C. LEE2   

  1. 1. The Key Laboratory of Analytical Sciences of the Ministry of Education and Department of Chemistry, Xiamen University, Xiamen, 361005;
    2. Department of Chemistry, Hong Kong Baptist University, Hong Kong
  • Online:2000-12-31 Published:2000-12-31
  • Supported by:

    Supported by the National Natural Science Foundation of China (29875024, 29735160).

PDF (PC)

被引次数

19

摘要：

Cinnabar, composed mainly of HgS,is often used in Traditional Chinese Medicines as part of the active ingredients in formulated drugs to treat diseases such as epilepsy,sore throat. To gain understanding on the clinical efficacy, safety and toxicity of these TCMs, information regarding not only the total concentrations of the heavy metals, but also their different chemical species is necessary. Therefore, the development of sample treatment and analytical techniques for the accurate determination and speciation of heavy metals in TCM products are of critical importance. The dual objectives of this work are to:(1) develop a leaching procedure using simulated body fluids for bioavailability and toxicity studies, and (2) investigate the possibility of Cinnabar derived mercury to bind with other constitutes in Tian Wan Bu Xin Wan using a sequential extraction scheme.

Abstract:

Cinnabar, composed mainly of HgS,is often used in Traditional Chinese Medicines as part of the active ingredients in formulated drugs to treat diseases such as epilepsy,sore throat. To gain understanding on the clinical efficacy, safety and toxicity of these TCMs, information regarding not only the total concentrations of the heavy metals, but also their different chemical species is necessary. Therefore, the development of sample treatment and analytical techniques for the accurate determination and speciation of heavy metals in TCM products are of critical importance. The dual objectives of this work are to:(1) develop a leaching procedure using simulated body fluids for bioavailability and toxicity studies, and (2) investigate the possibility of Cinnabar derived mercury to bind with other constitutes in Tian Wan Bu Xin Wan using a sequential extraction scheme.

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