高等学校化学学报

高等学校化学学报 ›› 2000, Vol. 21 ›› Issue (S1): 158.

• Chemistry in Life Sciences • 上一篇    下一篇

New Tetraazamacrocyclic Ligand with Neutral Pendent Groups 1,4,7,10-tetrakis (2-cyanoethyl)-l,4,7,10-tetraazacyclododecane (L) and Its Cobalt (Ⅱ), Nickel (Ⅱ) and Copper (Ⅱ) Complexes:Synthesis, Structural Characterization and Antitumor Activities

KONG De-Yuan1, XIE Yu-Yuan2   

  1. 1. Department of Chemistry, TEXAS A & M university, College Station, TEXAS 77842-3012, USA;
    2. Shanghai Institute of Materia/Medica, Chinese Academy of Sciences, Taiyuan Road 294, Shanghai, 200031
  • 出版日期:2000-12-31 发布日期:2000-12-31

New Tetraazamacrocyclic Ligand with Neutral Pendent Groups 1,4,7,10-tetrakis (2-cyanoethyl)-l,4,7,10-tetraazacyclododecane (L) and Its Cobalt (Ⅱ), Nickel (Ⅱ) and Copper (Ⅱ) Complexes:Synthesis, Structural Characterization and Antitumor Activities

KONG De-Yuan1, XIE Yu-Yuan2   

  1. 1. Department of Chemistry, TEXAS A & M university, College Station, TEXAS 77842-3012, USA;
    2. Shanghai Institute of Materia/Medica, Chinese Academy of Sciences, Taiyuan Road 294, Shanghai, 200031
  • Online:2000-12-31 Published:2000-12-31

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摘要：

A new tetraazamacrocyclic ligand (L) with four neutral 2-cyanoethyl pendent groups and its divalent transition-metal complexes:[Co(L)(NO3)]NO3·H2O (1),[Ni(L)(NO3)]NO3·3H2O (2) and[Cu(L)(H2O)](NO3)2 (3) have been synthesized. The crystal structures of (1) and (3) have been determined by X-ray analysis. In complex (1) the cobalt atom is coordinated by four nitrogen atoms and two oxygen atoms of a nitrate anion, which define a distorted octahedron. The other nitrate ion lies in the lattice as a counter ion.

Abstract:

A new tetraazamacrocyclic ligand (L) with four neutral 2-cyanoethyl pendent groups and its divalent transition-metal complexes:[Co(L)(NO3)]NO3·H2O (1),[Ni(L)(NO3)]NO3·3H2O (2) and[Cu(L)(H2O)](NO3)2 (3) have been synthesized. The crystal structures of (1) and (3) have been determined by X-ray analysis. In complex (1) the cobalt atom is coordinated by four nitrogen atoms and two oxygen atoms of a nitrate anion, which define a distorted octahedron. The other nitrate ion lies in the lattice as a counter ion.

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