高等学校化学学报

高等学校化学学报 ›› 2000, Vol. 21 ›› Issue (S1): 150.

• Chemistry in Life Sciences • 上一篇    下一篇

Studies on the Interaction of Ru(Ⅱ) Polypyridyl Mixed-ligand Complexes and DNA by Viscosity Measurement

HE Xiao-Feng, JI Liang-Nian   

  1. 1. Department of Physics, Chemistry and Biology, Shenzhen Education College, Shenzhen 518029;
    2. Department of Chemistry, Zhongshan University, Guangzhou 510275
  • 出版日期:2000-12-31 发布日期:2000-12-31

Studies on the Interaction of Ru(Ⅱ) Polypyridyl Mixed-ligand Complexes and DNA by Viscosity Measurement

HE Xiao-Feng, JI Liang-Nian   

  1. 1. Department of Physics, Chemistry and Biology, Shenzhen Education College, Shenzhen 518029;
    2. Department of Chemistry, Zhongshan University, Guangzhou 510275
  • Online:2000-12-31 Published:2000-12-31

PDF (PC)

摘要：

The interaction of transition metal polypyridyl coordination compounds with DNA has been extensively studied in the past few years[1]. Li the case of double stranded DNA, some coordination compounds may bind in the major groove with one ligand inserting between two base pairs DNA. The viscosity studies provide a strong argument for intercalation[2].

Abstract:

The interaction of transition metal polypyridyl coordination compounds with DNA has been extensively studied in the past few years[1]. Li the case of double stranded DNA, some coordination compounds may bind in the major groove with one ligand inserting between two base pairs DNA. The viscosity studies provide a strong argument for intercalation[2].

TrendMD: