高等学校化学学报 ›› 1998, Vol. 19 ›› Issue (S1): 470.

• Physical Organic Chemistry • 上一篇    下一篇

Hydrolysis of Lipophilic Amino Acid Esters Catalyzed by Metallomicelles

Xiao-Qi Yu, Jing Song You, Qing-Xiang Xiang, Qian-Shun Yan, Ru-Gang Xie   

  1. Department of Chemistry, Sichuan University, Chengdu 610064
  • 出版日期:1998-12-31 发布日期:1998-12-31
  • 基金资助:
    NSFC (No.29502008)

Hydrolysis of Lipophilic Amino Acid Esters Catalyzed by Metallomicelles

Xiao-Qi Yu, Jing Song You, Qing-Xiang Xiang, Qian-Shun Yan, Ru-Gang Xie   

  1. Department of Chemistry, Sichuan University, Chengdu 610064
  • Online:1998-12-31 Published:1998-12-31
  • Supported by:
    NSFC (No.29502008)

摘要: Metallomicelles as the model of hydrolytic metalloenzymes have begun recently1. Examples are the metal-ion complexes of lipophilic imidazoles2 and pyridines3 co-micelled with surfactants. Herein we report the complexes of a novel macrocyclic 12-membered di-oxotetraamine ligand bearing bis-hydroxy groups as functional pendants which can mimic the catalytic function of carboxypeptidase A in micellar media.

关键词: metallomicelles, lipophilic complexes, amino acid esters, hydrolysis

Abstract: Metallomicelles as the model of hydrolytic metalloenzymes have begun recently1. Examples are the metal-ion complexes of lipophilic imidazoles2 and pyridines3 co-micelled with surfactants. Herein we report the complexes of a novel macrocyclic 12-membered di-oxotetraamine ligand bearing bis-hydroxy groups as functional pendants which can mimic the catalytic function of carboxypeptidase A in micellar media.

Key words: metallomicelles, lipophilic complexes, amino acid esters, hydrolysis

TrendMD: