高等学校化学学报 ›› 1998, Vol. 19 ›› Issue (S1): 466.

• Physical Organic Chemistry • 上一篇    下一篇

Synthesis and Molecular Recognition of Novel Cleft-type Receptors

Shu-hua Chen, Dong-Hong Li, Fang Li, Hua-Ming Zhao   

  1. Department of chemistry, Sichuan University, Chengdu 610064
  • 出版日期:1998-12-31 发布日期:1998-12-31
  • 基金资助:
    National Natural Science Foundation of China

Synthesis and Molecular Recognition of Novel Cleft-type Receptors

Shu-hua Chen, Dong-Hong Li, Fang Li, Hua-Ming Zhao   

  1. Department of chemistry, Sichuan University, Chengdu 610064
  • Online:1998-12-31 Published:1998-12-31
  • Supported by:
    National Natural Science Foundation of China

摘要: A novel type of molecular cleft has been designed and synthesized from estrogen and approprite spacer groups such as xylylene or pyridine dimethylene. These receptor compounds 1a-d and 2a-d have been characterized by Mass spectra,1H-NMR spectra,IR spectra and elemental analyses. The structures of the receptors are shown in scheme 1. Their molecular recognition properties for the aromatic amine and aromatic amino acids have been investigated by UV-visble spectrophotometric titration. The titration data were analyzed by using the Benesi-Hildebrand equation[1].

Abstract: A novel type of molecular cleft has been designed and synthesized from estrogen and approprite spacer groups such as xylylene or pyridine dimethylene. These receptor compounds 1a-d and 2a-d have been characterized by Mass spectra,1H-NMR spectra,IR spectra and elemental analyses. The structures of the receptors are shown in scheme 1. Their molecular recognition properties for the aromatic amine and aromatic amino acids have been investigated by UV-visble spectrophotometric titration. The titration data were analyzed by using the Benesi-Hildebrand equation[1].

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