高等学校化学学报

高等学校化学学报 ›› 1998, Vol. 19 ›› Issue (S1): 381.

• Organometallic Chemistry • 上一篇    下一篇

Resolution of Cycloplatinated Ferrocenylketimines

Wu Yang-Jie, Ding Li, Wang Wen-Ling, Du Chen-Xia, Song Qiu-Ling   

  1. Department of Chemistry, Zhengzhou University, Zhengzhou 450052
  • 出版日期:1998-12-31 发布日期:1998-12-31

Resolution of Cycloplatinated Ferrocenylketimines

Wu Yang-Jie, Ding Li, Wang Wen-Ling, Du Chen-Xia, Song Qiu-Ling   

  1. Department of Chemistry, Zhengzhou University, Zhengzhou 450052
  • Online:1998-12-31 Published:1998-12-31

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摘要： Ferrocene derivatives especially the chiral and optically active 1,2-disubstituted ferrocenes are the most extensively investigated metallocenes. The common way to obtain the planar chirality in the ferrocene moiety is the usage of a chiral precursor. Sokolov et al have reported the asymmetric cyclopalladation with the salts of optically active carboxylic acids as nucleophilic catalysts, however, this method was suitable only when the reaction experienced the diastereomeric transition states[1]. The only report,of the resolution of cyclometallated ferrocene derivatives was given by Nonoyama and his coworkers[2]. They resolved dimethyl-aminomethylferrocene to optically pure enantiomers using the (S)-proline as chiral auxiliary and separated the diastereomers by solubility difference.

Abstract: Ferrocene derivatives especially the chiral and optically active 1,2-disubstituted ferrocenes are the most extensively investigated metallocenes. The common way to obtain the planar chirality in the ferrocene moiety is the usage of a chiral precursor. Sokolov et al have reported the asymmetric cyclopalladation with the salts of optically active carboxylic acids as nucleophilic catalysts, however, this method was suitable only when the reaction experienced the diastereomeric transition states[1]. The only report,of the resolution of cyclometallated ferrocene derivatives was given by Nonoyama and his coworkers[2]. They resolved dimethyl-aminomethylferrocene to optically pure enantiomers using the (S)-proline as chiral auxiliary and separated the diastereomers by solubility difference.

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