高等学校化学学报 ›› 1998, Vol. 19 ›› Issue (S1): 355.
• Organometallic Chemistry • 上一篇 下一篇
Liu Hua, Chen Xue-Ren, Wang Ji-Tao, Xie Qing-Lan, Li Jing
Liu Hua, Chen Xue-Ren, Wang Ji-Tao, Xie Qing-Lan, Li Jing
摘要: The drug molecule is called as silα-drug if one carbon atom is substituted by silicon atom in the organic-drugs. Generally, drugs of this kind have low toxicity and pro-long efficiency. People have designed many methods in order to decrease the toxicity of organotin compounds and organosilicon has proved to be effective. Torque[1] is a new acaricide made by Shell company in America, its structure is[(PhMe2CCH2)3SnI2O. R. Tacke[2] from Germany synthesized the compounds (PhMe2SiCH2)3SnX[X=HO, (PhMe2SiCH2)3SnO] and tested the acaricidal activity of[(PhMe2EICH2)3Sn]2O (EI=C, Si) in 1986. He proved that the silyl-derivatives of Torque were highly effective acaricides.
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