高等学校化学学报

高等学校化学学报 ›› 1998, Vol. 19 ›› Issue (S1): 283.

• Organic Synthesis Chemistry • 上一篇    下一篇

A NEW METHOD OF SYNTHESIS β-D-MANNOPYRANOSIDE BY STEREOCONTROLLED PROCEDURE

Jian-Xin YU1, Fang-Min LIU1, Jin-Xiu SU1, Wen-Jie LU1, Yan-Ping LI1, Yu-Ting LIU1, Xu-Li TANG2, Ying DONG3, Meng-Shen CAI3   

  1. 1. Department of Chemistry, Xinjiang University, Ulumuqi, 830046;
    2. Central Analytical Lab, Xinjiang Chinese Medical Factory, Ulumuqi 830001;
    3. School of Pharmaceutical Sciences, Beijing Medical University, Beijing 100083
  • 出版日期:1998-12-31 发布日期:1998-12-31

A NEW METHOD OF SYNTHESIS β-D-MANNOPYRANOSIDE BY STEREOCONTROLLED PROCEDURE

Jian-Xin YU1, Fang-Min LIU1, Jin-Xiu SU1, Wen-Jie LU1, Yan-Ping LI1, Yu-Ting LIU1, Xu-Li TANG2, Ying DONG3, Meng-Shen CAI3   

  1. 1. Department of Chemistry, Xinjiang University, Ulumuqi, 830046;
    2. Central Analytical Lab, Xinjiang Chinese Medical Factory, Ulumuqi 830001;
    3. School of Pharmaceutical Sciences, Beijing Medical University, Beijing 100083
  • Online:1998-12-31 Published:1998-12-31

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摘要： The β-D-mannopyranoside bond is an important structural element of N-glycoproteins, widespread in multicellular organisms as serum, cytosol, and membrane compounds[1]. However, as both the neighboring group assistance and steric repulsion as well as the anomeric effect uniformly favor the formation of α-D-mannopyranoside, the β-D-mannopyranosyl linkage still remains especially difficult to be constructed.

Abstract: The β-D-mannopyranoside bond is an important structural element of N-glycoproteins, widespread in multicellular organisms as serum, cytosol, and membrane compounds[1]. However, as both the neighboring group assistance and steric repulsion as well as the anomeric effect uniformly favor the formation of α-D-mannopyranoside, the β-D-mannopyranosyl linkage still remains especially difficult to be constructed.

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