高等学校化学学报

高等学校化学学报 ›› 1998, Vol. 19 ›› Issue (S1): 234.

• Organic Synthesis Chemistry • 上一篇    下一篇

Synthesis of Phosphopeptides with Enzymatic Protecting Group

Yan-Mei LI, Yu-Fen Zhao, Herbert Waldmann   

  1. 1. Department of Chemistry, Tsinghua University, Beijing 100084;
    2. Institut fuer Organische Chemie, Universitaet Karlsruhe, Richard-Willstaetter-Allee 2, 76128 Karlsruhe, Germany
  • 出版日期:1998-12-31 发布日期:1998-12-31

Synthesis of Phosphopeptides with Enzymatic Protecting Group

Yan-Mei LI, Yu-Fen Zhao, Herbert Waldmann   

  1. 1. Department of Chemistry, Tsinghua University, Beijing 100084;
    2. Institut fuer Organische Chemie, Universitaet Karlsruhe, Richard-Willstaetter-Allee 2, 76128 Karlsruhe, Germany
  • Online:1998-12-31 Published:1998-12-31

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摘要： Reversible protein phosphorylation is widely recognized as an important mechanism for the regulation of many cellular processe[1]. For the study of the roles of the phosphoproteins in biological processes, structurally well-defined compounds are often needed, which contain the characteristic structural units of the parent biomacromolecules, i.e. the linkage regions between the peptide chain and phosphoric acid esters.

Abstract: Reversible protein phosphorylation is widely recognized as an important mechanism for the regulation of many cellular processe[1]. For the study of the roles of the phosphoproteins in biological processes, structurally well-defined compounds are often needed, which contain the characteristic structural units of the parent biomacromolecules, i.e. the linkage regions between the peptide chain and phosphoric acid esters.

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