高等学校化学学报

高等学校化学学报 ›› 1998, Vol. 19 ›› Issue (S1): 166.

• Organic Synthesis Chemistry • 上一篇    下一篇

Facile Synthesis of 6β-Hydroxy-7α(H)-eudesma-4-en-3-one and β-Cyperone

Gang ZHOU1,2, Zhao Ming XIONG1, Yong Gang CHEN1, Yu Lin Ll1,2   

  1. 1. National Laboratory of Applied Organic Chemistry and Institute of Organic Chemistry, Lanzhou University, Lanzhou 730000;
    2. National Laboratory of Elemento-Organic Chemistry at Nankai University
  • 出版日期:1998-12-31 发布日期:1998-12-31
  • 基金资助:
    National Natural Science Foundation of China (Grant No. 29732060) and National Laboratory of Elemento-Organic Chemistry at Nankai University

Facile Synthesis of 6β-Hydroxy-7α(H)-eudesma-4-en-3-one and β-Cyperone

Gang ZHOU1,2, Zhao Ming XIONG1, Yong Gang CHEN1, Yu Lin Ll1,2   

  1. 1. National Laboratory of Applied Organic Chemistry and Institute of Organic Chemistry, Lanzhou University, Lanzhou 730000;
    2. National Laboratory of Elemento-Organic Chemistry at Nankai University
  • Online:1998-12-31 Published:1998-12-31
  • Supported by:
    National Natural Science Foundation of China (Grant No. 29732060) and National Laboratory of Elemento-Organic Chemistry at Nankai University

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摘要： Eudesmane derivatives have been drawing considerable attention due to their wide spectrum of biological proerties, particulaly antifeedant, cell growth inhibitory and plant growth regulating activities.1 In recent years a number of C-6 oxyfunctionalized eudesmanes and β-dihydroagarofurans,such as compounds 3-6,have been isolated from nature sources. However the reports on the synthesis of this particular kind of compounds are few and the reported syntheses are generally by synthetic methodology starting from α-santonin 22. Our interest of study on the synthesis of this kind of compounds prompted us to investigate a new synthetic route from cheap material (+)-dihydrocarvone 7.

Abstract: Eudesmane derivatives have been drawing considerable attention due to their wide spectrum of biological proerties, particulaly antifeedant, cell growth inhibitory and plant growth regulating activities.1 In recent years a number of C-6 oxyfunctionalized eudesmanes and β-dihydroagarofurans,such as compounds 3-6,have been isolated from nature sources. However the reports on the synthesis of this particular kind of compounds are few and the reported syntheses are generally by synthetic methodology starting from α-santonin 22. Our interest of study on the synthesis of this kind of compounds prompted us to investigate a new synthetic route from cheap material (+)-dihydrocarvone 7.

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