高等学校化学学报 ›› 1998, Vol. 19 ›› Issue (S1): 162.
• Organic Synthesis Chemistry • 上一篇 下一篇
Zuo Sheng LIU, Chu Sheng HUANG, Jiong LAN, Yu Lin LI
Zuo Sheng LIU, Chu Sheng HUANG, Jiong LAN, Yu Lin LI
摘要: Some Ligularia species have long used as folk remedies due to their antibiotic, antiphlogistic and antitumor activities.1 Compound 1,2 a novel coniferyl alcohol, was isolated from ligularia duciformis(Compoitae). The geometrical structure of 1,determined by spectroscopic techniques, was corresponded to 4-o-(6,-hydroxy-7'(9')-dehydro-6',7'-dihydrogeranyl)-coniferyl alcohol. But its absolute configuration at C-6,has not yet been determined. Herein, we report the total synthesis of (6'S)-(-)-1 from Geraniol 2 through 9 steps (Scheme 1).
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