高等学校化学学报 ›› 1989, Vol. 10 ›› Issue (9): 881.

• 研究论文 •    下一篇

硫代脯氨酸含硼配合物研究

袁国正, 黄俊杰, 张国敏   

  1. 武汉大学化学系
  • 收稿日期:1988-01-20 出版日期:1989-09-24 发布日期:1989-09-24
  • 通讯作者: 袁国正

Diaryl Boron Chelates of Thioproline

Yuan Guozheng, Huang Junjie, Zhang Guomin   

  1. Department of Chemistry, Wuhan University, Wuhan
  • Received:1988-01-20 Online:1989-09-24 Published:1989-09-24

摘要: 具有抗癌作用的硫代脯氨酸可作为双齿配体与具有类金属属性的二芳基硼形成螫合物.本文报道9种这类新配合物,研究了IR、MS、NMR波谱.除配合物2和9外,这类配合物大都产生由于明显的芳基偶联作用而出现的碎片峰.

关键词: 氨基酸衍生物, 有机硼化合物, 杂环化合物, 螯合物, 四氢噻唑-4-羧酸, 硫代脯氨酸

Abstract: Thioproline which can induce the cancer cells to lose the characteristics of tumoral transformation unites with diaryl boron group, forming pseudometal-chelated compound.The structures of nine compounds were confirmed by elemental analysis,and IR,MSand NMRspectrometries.

Key words: Organoboron compound, Heterocyclic compound, Chelate compound, Thiazolidine-4-car-boxylic acid, Thioproline

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