Chem. J. Chinese Universities ›› 1993, Vol. 14 ›› Issue (5): 656.

• Articles • Previous Articles     Next Articles

Gas Chromatographic-Mass Spectrometric Detection of Methylphenidate's Metabolite in Urine

CUI Kai-Rong1, ZHANG Chang-Jiu1, WANG Shan1, CHEN Shi-Zhi2   

  1. 1. National Research Institute of Sports Medicine, State Sports Commission, Beijing, 100029;
    2. Peking Union Medical College, Beijing, 100050
  • Received:1992-11-10 Revised:1993-02-22 Online:1993-05-24 Published:1993-05-24

Abstract: Arapid sensitive method has been developed for the detection of the metabolite (ritalinic acid) of methylphenidate in urine by using GC-MSD.The derivatization agents are MSTFAand MBT-FA.The recovery and detection limit are 77.2%±2.l%(n= 4) and 3 ng, respectively.This method is fit to detect the methylphenidate in doping control.

Key words: Methylphenidate, Ritalinic acid, GC-MSD, Doping control

TrendMD: