Abstract: 2-Alkyl-1,4-dimethoxybenzenes (1_a-d) react with both concentrated HNO₃ and NH₄NO₃ in glacial acetic acid to form only simple nitrated products,2-alkyl-5-nitro-1,4dimethoxybenzenes (4_a-d).However, in the case of 2-alkyl-5-t-butyl-1,4-dimethoxvbenzenes (2_a-d) or 2,5-di-t-butyl-1, 4-dibenzoxybenzene (3), the formation of products greatly depends upon both the properties of the employed nitrating agents and the structures of these reactants.According to the observed resultsk, two possibilities for the reactions mechanism are proposed.

Key words: Aromatic nitration, p-Dialkoxybenzene, Single electron transfer, Ipso-de-tbutylation