Chem. J. Chinese Universities ›› 1999, Vol. 20 ›› Issue (2): 199.

• Articles • Previous Articles     Next Articles

HELP Applied to Traditional Chinese Medicine Analysis Determination of Components of Cordyceps Sinensis

GONG Fan1, PENG Yuan-Gui2, CUI Hui1, LIANG Yi-Zeng1, Alexander K.M.Leung3, Foo-timChau3   

  1. 1. College of Chemistry and Chemical Engineering, Institute of Chemometrics and Chemical Sensing Technology, Hunan University, Changsha, 10082;
    2. Institute of Materia Medica, Hunan Academy of Tradition Chinese Medicine&Materia Medica, Chang sha, 410082;
    3. Open Laboratory of A symmetric Sythesis, Departmemt of Applied Biology and Chemical Technology, Hong Kong Poly technic University, Kowloon, Hong Kong
  • Received:1998-06-08 Online:1999-02-24 Published:1999-02-24

Abstract: The multicomponent qualitative and quantitative analysis of Stroma and Caterpillar body of Cordyceps sinensis were carried out by Heuristic Evolving Latent Projection(HELP) method. The procedure for resolving the twoway chromatogram/spetrum data obtained from the hyphenated instruments with HELP was developed in detail. It showed that HELP method could be used to examine the purity of chromatographic peaks, resolve overlapping peaks and finally obtain the pure chromatographic profiles and spectra for all the chemical components in the studied system. The separation ability of chromatography can be greatly improved. Moreover, the accuracy of qualitative and quantitative results could also be enhanced by means of this method. HELP method could be a promising method to the simultaneous multicomponent analysis for traditional chinese medicine.

Key words: Heuristic evolving latent projections, Cordyceps sinensis, Multicomponent analysis

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