Determination of the Volatile Chemical Constituents of Notoptergium Incium by GC-MS and OPA or EWOP

Abstract

Abstract: The qualitative and quantitative determination of the chemical constituents in traditional Chinese medicines(TCMs) is an important task, which builds the foundation of the theory of pharmacological activity. The hyphenated chromatographic instruments combined with the related chemometric methods provide powerful tools for the resolution of such complex systems. The volatile chemical constituents of Notoptergium incium (NI) were analyzed by gas chromatography mass spectrometry(GC MS) and the overlapped peaks were resolved into pure chromatograms and pure spectra with iterative OPA or non iterative EWOP chemometrics resolution method. Sixty five of the 98 separated constituents in essential oil of Notoptergium incium , accounting for 92.13%, were identified and quantified by the developed method.

Key words: Gas chromatography mass spectrometry(GC MS), Evolving window orthogonal projection(EWOP), Orthogonal projection approach(OPA), Notoptergium incium (NI), Volatile oil

CLC Number:

O657

TrendMD:

GUO Fang-Qiu, LIANG Yi-Zeng, HUANG Lan-Fang, XU Cheng-Jian . Determination of the Volatile Chemical Constituents of Notoptergium Incium by GC-MS and OPA or EWOP[J]. Chem. J. Chinese Universities, 2004, 25(3): 430.

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