Chem. J. Chinese Universities ›› 2010, Vol. 31 ›› Issue (6): 1137.

• Articles • Previous Articles     Next Articles

Studies on Chemical Constituents of Compound Indigowoad Root Granule by Mass Spectrometry

LIU Shu1,3, YAN Jun2, LI Hui-Lin1, SONG Feng-Rui1, LIU Zhong-Ying2, LIU Zhi-Qiang1*, LIU Shu-Ying1   

  1. 1. Changchun Center of Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China;
    2. School of Pharmacy, Jilin University, Changchun 130021, China;
    3. Graduate School of the Chinese Academy of Sciences, Beijing 100049, China
  • Received:2009-10-26 Online:2010-06-10 Published:2010-06-10
  • Contact: LIU Zhi-Qiang. E-mail: liuzq@ciac.jl.cn
  • Supported by:

    国家科技支撑计划项目(批准号: 2006BAI08B03-02)资助.

Abstract:

Muti-tandem electrospray ionization mass spectrometry(ESI-MSn) and Fourier transform ion cyclotron resonance mass spectrometry(FT-ICR-MS) have been applied to analyse the chemical constituents from water and 95% ethanol extract of Compound Indigowoad Root Granule. A number of compounds were identified including amino acid, sugar and their derivatives, organic acid, primary products of the Maillard reaction of amino acid with monosaccharide and epigoitrin. This method is sensitive and rapid, suitable for analyzing the chemical composition of traditional Chinese medicine extract.

Key words: Compound Indigowoad Root; Chemical constituent; Muti-tandem electrospray ionization mass spectrometry(ESI-MSn); Fourier transform ion cyclotron resonance mass spectrometry(FT-ICR-MS)

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