Different Materials Coated Magnetic Nanoparticles Studied by Home-made Surface Plasmon Resonance Sensor

Chem. J. Chinese Universities ›› 2009, Vol. 30 ›› Issue (5): 882.

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Different Materials Coated Magnetic Nanoparticles Studied by Home-made Surface Plasmon Resonance Sensor

TAO Lei^1,2, JIN Wei¹*, ZHANG Ying^1,2, YAN Fei², WANG Lin-Lin^1,2, MU Ying^1,2*, JIN Qin-Han^1,3

1. Research Center for Analytical Instrumentation, Institute of Cyber-Systems and Control, State Key Laboratory of Industrial Control Technology, Zhejiang University, Hangzhou 310058, China;
2. Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun 130021, China;
3. College of Chemistry, Jilin University, Changchun 130012, China

Received:2009-01-07 Online:2009-05-10 Published:2009-05-10
Contact: MU Ying, E-mail: ymu100@yahoo.com.cn; JIN Wei, E-mail: jinweimy@gmail.com

Abstract

Abstract:

By means of surface plasmon resonance(SPR) sensor with a light emission diode(LED) as the excitation source, the association degree of the target DNA coupled with different materials coated magnetic nanoparticles with biotinylated DNA probe was investigated. Compared with that of target DNA coupled with magnetic polystyrene microspheres with biotinylated DNA probe, the association of target DNA conjugated with silica-coated magnetic nanoparticles was faster and the RSD was smaller.

Key words: Surface plasmon resonance sensor, Magnetic nanoparticles, Biotinylated DNA probe, Target DNA

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TAO Lei, JIN Wei*, ZHANG Ying, YAN Fei, WANG Lin-Lin, MU Ying, ....... Different Materials Coated Magnetic Nanoparticles Studied by Home-made Surface Plasmon Resonance Sensor[J]. Chem. J. Chinese Universities, 2009, 30(5): 882.

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Different Materials Coated Magnetic Nanoparticles Studied by Home-made Surface Plasmon Resonance Sensor

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