Chem. J. Chinese Universities ›› 2006, Vol. 27 ›› Issue (5): 885.doi:
Previous Articles Next Articles
CHA RuiTao, DU Tian, YUAN Zhi*
Received:
Revised:
Online:
Published:
Contact:
Abstract:
tarted from the liver targeting compounds(glycyrrhizin, glycyrrhetinicacid, bile acid), six amine-terminated compounds were prepared via two-step reactions. The NMR experiments provided the direct evidence of the existence of amide. The polymers were synthesized by polymerizing of BLG-NCA initiated by each of six amineterminated compounds. The liver targeting group was introduced to the main chain of the polymer. The molecular weight of the resultant polymers was adjusted by changing the molar ratio of monomer BLG-NCA to initiator. The product structure was characterized by GPC, FTIR and 1 H NMR. The results demonstrate that amine-terminated compounds containing liver targeting group could initiate the polymerization of BLG-NCA.
Key words: Target of liver; Glycyrrhizin; Glycyrrhetinic acid; Bile acid; Poly(γ-benzyl-L-glutamate)
CLC Number:
Q592.1
TrendMD:
CHA RuiTao, DU Tian, YUAN Zhi*. Syntheses and Characterization of Poly(γ-benzyl-L-glutamate) Containing Liver Targeting Group in Main Chain[J]. Chem. J. Chinese Universities, 2006, 27(5): 885.
0 / / Recommend
Add to citation manager EndNote|Ris|BibTeX
URL: http://www.cjcu.jlu.edu.cn/EN/
http://www.cjcu.jlu.edu.cn/EN/Y2006/V27/I5/885
