Design, Synthesis and Herbicidal Activity of Novel Sulfonylureas Containing Monosubstituted Pyrimidine Moiety

doi:10.7503/cjcu20120972s

Abstract

Abstract:

Sulfonylureas, a unique group of herbicides, were extensively applied to controlling a range of weeds in a variety of crops and vegetables. In order to find efficient sulfonylurea herbicides, the title compounds were designed by introducing monosubstituted pyrimidinamines into some well-known sulfonylurea skeletons. A series of sulfonylurea compounds were synthesized and characterized by ¹H NMR and HRMS. Herbicidal activities and IC₅₀ values of the title compounds were determined by Pot plant test and Petri dish test against Brassica napus, Amaranthus retroflexus, Echinochloa crusgalli and Digitaria adscendens. Some compounds exhibited herbicidal activities. Compounds 7b and 7d possessed significant inhibition effects against Brassica napus and Amaranthus retroflexus. Further structural modification of novel sulfonylureas containing monosubstituted pyrimidine moiety will be required for improving efficacy against weeds in our lab.

Key words: Sulfonylurea, Monosubstituted pyrimidine, Herbicidal activity

CLC Number:

O626.41

TrendMD:

PAN Li, LIU Zhuo, CHEN You-Wei, LI Yong-Hong, LI Zheng-Ming. Design, Synthesis and Herbicidal Activity of Novel Sulfonylureas Containing Monosubstituted Pyrimidine Moiety[J]. Chem. J. Chinese Universities, 2013, 34(6): 1416.

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Design, Synthesis and Herbicidal Activity of Novel Sulfonylureas Containing Monosubstituted Pyrimidine Moiety

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