Chem. J. Chinese Universities ›› 1986, Vol. 7 ›› Issue (6): 508.
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Zhuo Renxi, Fan Changlie, Zhao Rulin
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Abstract: Twelve 5-fluorouracil amino acid derivatives were synthesized by the condensation of p-nitrophenyl 5-fluorouracil -1-ylacetate or p-nitrophenyl 5-fluorouracil -1-ylpropionate with a series of amino acids in alkaline DMF-H2 Osolvent. The structures of these new compounds were examined by IR, 1H NMRand UVspectra as well as elemental analysis. Animal screening data showed that some of the compounds exhibit certain antitumor activity .
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Zhuo Renxi, Fan Changlie, Zhao Rulin . Synthesis and Antitumor Activity of 5-Fluorouracil Containing Amino Acid Derivatives[J]. Chem. J. Chinese Universities, 1986, 7(6): 508.
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http://www.cjcu.jlu.edu.cn/EN/Y1986/V7/I6/508
