Abstract: In the past few years several sesquiterpenes had been isolated from this family compositae. On the basic of the previous work, four furoeremophilanes were also isolated from Senecio kaschkarovii. Their structures, were identified as 1α-acetoxy-6β-angeloyloxy-10β-hydroxy-9-oxofuroeremophilane(1); 1α-methacryloyloxy-6β-Acetoxy-10β-hydroxy-9-oxofuroeremophilane(2); 6β-isobutyloxy-10(1)-en-9-oxofuroeremophilane(3); 1β-acetoxy-6β-acetoxy-10β-H-9-oxofuroeremophilane(4) by means of spectroscopic techniques(UV, IR, NMR, MS, CD) and chemical properties. Compound 3 was obtained from Senecio kaschkarovii for the first time. Compound 4 was a new compound, and its absolute configuration was determined.

Key words: Senecio kaschkarovii, Compositae, Furoeremophilane