Abstract: Eighteen new O-3-(2'- or 4' -pyridyl)propyl phosphoronates (Ⅰ), phospho-roamidothionates (Ⅱ) and phosphonothionates (Ⅲ) were prepared by condensing 3-(2'-or 4-pyridyl) propanol with O, O-dialkylphosphorochloridothionates(1) O-alkylphosphoroamidochloridothionates (2) and O-alkyl (or aryl)phenylphos-phonochloridothionates(3), respectively, in presence of a base. The favourable reaction conditions and the purification methods of these compounds were found out. Their 1R and ¹HNMR spectra data were given. The results of the primary biological tests showed that some of the compounds enhanced and some inhibited the growth of the coleptiles of wheat.