Titration Calorimetry Study on the Protonation Reaction of α-Carboxyl Group of Ammo Acids

Chem. J. Chinese Universities ›› 1991, Vol. 12 ›› Issue (11): 1522.

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Titration Calorimetry Study on the Protonation Reaction of α-Carboxyl Group of Ammo Acids

Zhang Bao-lin¹, Wang Wen-qing¹, Li Zhong¹, Tao Zu-yi²

1. Department of Technical Physics, Peking University, Beijing, 100871;
2. Department of Modern Physics, Lanzhou University, Lanzhou

Received:1990-07-04 Online:1991-11-24 Published:1991-11-24

Abstract

Abstract: The thermodynamic functions of protonation reactions of α-carboxyl group of twelvekinds of amino acids--alanine?valine, lysine, leucine, phenylalanine, methionine, trypto-phan, threonine, serine, arginine, glutamic acid and glycine, have been determined by titration calorimetry combined with computer fit program. The differences between △H, AG, lgK, △Sof the protonation reactions of amino acids have been reported. By comparison with pHtitration method, it is simple, rapid and would be obtained simultaneously the total thermodynamic functions-IgK, △H, △G and △S.

Key words: Titration calorimetry, Arnino acid, Protonation reaction

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Zhang Bao-lin, Wang Wen-qing, Li Zhong, Tao Zu-yi. Titration Calorimetry Study on the Protonation Reaction of α-Carboxyl Group of Ammo Acids[J]. Chem. J. Chinese Universities, 1991, 12(11): 1522.

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Titration Calorimetry Study on the Protonation Reaction of α-Carboxyl Group of Ammo Acids

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