CJCU

Chem. J. Chinese Universities ›› 2009, Vol. 30 ›› Issue (9): 1744.

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Chiral Recognition of Mandelic Acid by Temperature Induced Double Aqueous Phases System

XING Jian-Min, LI Fen-Fang*   

  1. School of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China
  • Received:2009-01-12 Online:2009-09-10 Published:2009-09-10
  • Contact: LI Fen-Fang. E-mail: lfflqq@mail.csu.edu.cn
  • Supported by:

    湖南省自然科学重点基金(批准号: 08jj3023)和中南大学优秀博士学位论文(批准号: 2008yb036)资助.

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Abstract:

The partitioning behavior of mandelic acid was studied on the isopropyl alcohol/salt and TritonX-114 temperature induced system. The results show that the mandelic acid tends to exist in the isopropyl alcohol phase of the isopropyl alcohol/salt system, and in the water phase of the TritonX-114 temperature induced system, so the TritonX-114 temperature induced system was used as chiral recognition system. The chiral recognition of mandelic acid was investigated in the TritonX-114/n-amyl-L-tartrate/teasaponin and TritonX-114/β-CD system. Several factors were studied such as content of teasaponin, temperature. The results show that the TritonX-114/n-amyl-L-tartrate/teasaponin system is better than the TritonX-114/β-CD system. The separation factor increased with the teasaponin and temperature increased, and the optimal chiral recognition condition of double aqueous phases system was obtained, the content of teasaponin was 0.51 mmol, the n-amyl-L-tartrate was 1.4 mmol, temperature was 55 ℃. The largest separation factor was 1.29.

Key words: Double aqueous phases system; Chiral recognition; Temperature induced

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