Microwave-induced Synthesis and Spectral Properties of New 4-Hydroxycoumarin Derivatives

Chem. J. Chinese Universities ›› 2009, Vol. 30 ›› Issue (8): 1516.

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Microwave-induced Synthesis and Spectral Properties of New 4-Hydroxycoumarin Derivatives

DONG She-Ying^1*, LI Jing¹, HUANG Ting-Lin²

1. College of Sciences,
2. School of Environment and Municipal Engineering, Xi′an University of Architecture and Technology, Xi′an 710055, China

Received:2008-07-17 Online:2009-08-10 Published:2009-08-10
Contact: DONG She-Ying. E-mail: dongsyy@126.com
Supported by:
陕西省自然科学基础研究基金(批准号: 2005B28)资助.

Abstract

Abstract:

Three kinds of 4-hydroxycoumarin derivatives, 3,3′,3″,3″′-ethylenetetrakis-4-hydroxycoumarin(b), 3,3′-benzylidenedi-4-hydroxycoumarin(c) and 4-hydroxycoumarin-1,4-naphthaquinone(d) were synthesized from 4-hydroxycoumarin(a) under microwave irradiation and characterized by means of elemental analysis, IR, ¹H NMR and MS. The compounds a—d were studied by ultraviolet-visible absorption spectra and fluorescence spectroscopy. It was confirmed that the big π-conjugated, symmetrical compound b had better fluorescence in solution and possessed high molar extinction coefficient. When the concentration of compound b was in the range of 0.50—1.50×10^-4 mol/L, the fluorescence intensity linearly increased with decreasing concentration. In the range of pH=1.18—6.09, fluorescence intensity increased with increasing of pH, and in the range of pH=8.36—11.98 fluorescence intensity increased with decreasing of pH values. In addition, fluorescence enhancing was significantly observed in the presence of BSA and DNA.

Key words: 4-Hydroxycoumarin derivative; Microwave-induced synthesis; Ultraviolet-visible absorption spectra; Fluorescence spectrum

TrendMD:

DONG She-Ying*, LI Jing, HUANG Ting-Lin. Microwave-induced Synthesis and Spectral Properties of New 4-Hydroxycoumarin Derivatives[J]. Chem. J. Chinese Universities, 2009, 30(8): 1516.

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Microwave-induced Synthesis and Spectral Properties of New 4-Hydroxycoumarin Derivatives

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