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Chem. J. Chinese Universities

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Studies on the Difference Between Combination Reaction Enantiomeric Drugs
with Albumins by Using a New Home-made Surface Plasomon Resonance Sensor

ZOU Xiang-Yu, ZHOU Jian-Guang, FENG Guo-Dong, ZHANG Lei, LI Ming, JIN Qin-Han   

  1. Institute for Miniature Instrumentation, College of Chemistry, Jilin Pronince Research Center for Engineering and Technology of Spectral Instruments, Jilin University, Changchun 130023, China
  • Received:2005-11-15 Revised:1900-01-01 Online:2006-09-10 Published:2006-09-10
  • Contact: JIN Qin-Ha

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Abstract: Based on surface plasmon resonance(SPR), a novel optical chemical sensor for distinguishing enantiomeric drugs was developed. The difference between combination reaction of enantiomeric drugs with albumins was studied by using this setup. According to these differences the enantiomeric drugs can be distinguished. This method was shown to have many advantages in comparison with traditional methods. The major ones include the elimination of labeling and screening rapidly.

Key words: Surface plasomon resonance sensor, Enantiomeric drugs, Phenylglycin

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