Abstract: The asymmetric hydrosilylation of 2-amino aryl ketones catalyzed by [Rh(COD)Cl]₂/2-(2-pyridyl)-4-carbomethoxy-1,3-thiazolidine(A) systems was first reported. The chiral 2-amino-1-aryl ethanols were obtained in nearly quantatative yield and high enantioselectivity. The reaction of fourteen 2-amino arylketones with different groups were investigated. It was found that the %e.e.% values were all higher than 92% when there are group(s), such as OH, OM e or Me on the phenyl group,while the optical purities were less than 85% e.e. when there are group(s) such as Cl, NO₂ on the phenyl group. In comparision with the reaction of ketones having no founctional group, the optical yield of 2-amino ketones were higher.

Key words: Asymmetric hydrosilylation, Chiral 2-amino-1-aryl ethanol, Calalysis