Chem. J. Chinese Universities ›› 1999, Vol. 20 ›› Issue (6): 906.

• Articles • Previous Articles     Next Articles

Synthesis, Spectra and Stereochemistry of β-Lactam Derivatives of 1,5-Benzothiazepines

LI Yuan1, DU Cai-Yun2, YANG Qiu-Qing3, JIN Sheng4, XING Qi-yi4   

  1. 1. Department of Chemistrya, Hebei Normal Universitya, Shijiazhuang, 050016;
    2. Experiment Centerc, Hebei Normal Universitya, Shijiazhuang, 050016;
    3. Department of Chemistrya, Experiment Center, Hebei Normal Universitya, Shijiazhuang, 050016;
    4. Department of Basic Courseb, Handan Agricultural College, Handan, 057150
  • Received:1998-06-29 Online:1999-06-24 Published:1999-06-24

Abstract: Five title compounds were synthesized, their spectra and steric structures have been studied. The result reveals that the conformation of these compounds is chair-like, the chloro and phenyl substituents on C-2 and C-3 are cis to the fourmembered ring, the reaction of 1,5-benzothiazepine with chloroacelyl chloride is stereospecific reaction.

Key words: 1,5-Benzothiazepine, β-Lactam, Steric structure

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