The Relationshiop Between Bichiral Amino Alcohol(Salicylaldimino)Copper Complexes and Enantioselectivities of Cyclopropanation

Abstract

Abstract: The enantioselective cyclopropanation of olefins olefins and ethyl diazoacetate underbichral amino alcohol salicylaldimino-copper complexes was studied.The resuls show thatthe main effect on the enantioselectivity is the configuration of the carbon attached to nitro-gen atom,the R-(N-C)-configuration catalyst produces the excess of the 1R-cyclopropaneproduct and the S-(N-C)-configuration catalyst produces the excess of the 1S-cyclopropaneproduct.The configuration of the carbon attached to oxygen atom also has effect on theenantioselectivety of reaction, but this is not the major one.

Key words: Chirality, Copper(Ⅱ)complexes, Cyclopropanation

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WANG Min, NU Bing-Fang, W. Kraus. The Relationshiop Between Bichiral Amino Alcohol(Salicylaldimino)Copper Complexes and Enantioselectivities of Cyclopropanation[J]. Chem. J. Chinese Universities, 1996, 17(1): 65.

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The Relationshiop Between Bichiral Amino Alcohol(Salicylaldimino)Copper Complexes and Enantioselectivities of Cyclopropanation

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