Studies on the Synthesis and Biological Activities of Aryl Amidoximyl Chrysanthemumates and 1,2,4-Oxadiazole Derivatives

Chem. J. Chinese Universities ›› 1994, Vol. 15 ›› Issue (7): 1009.

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Studies on the Synthesis and Biological Activities of Aryl Amidoximyl Chrysanthemumates and 1,2,4-Oxadiazole Derivatives

JIN Gui-Yu, ZHAO Guo-Feng, ZHENG Jian-Yu

Institute of Elemento-Organic Chemistry, Nankai Univcrsity, Tianjin, 300071

Received:1993-08-26 Revised:1994-03-22 Online:1994-07-24 Published:1994-07-24

Abstract

Abstract: Aryl amidoximes reacted with substituted cyclopropane carbonyl chlorides under the action of Et₃Nin room temperature to give aryl amidoximyl chrysanthemumates and under reflux in toluene to give 1, 2, 4-oxadiazole derivatives.When the formers reacted under reflux in toluene using HOAc as catalysis, the cyclization took place and 1, 2, 4-oxadiazole derivatives were also obtained.The preliminary biological tests indicated that these compounds had fungicidal and herbicidal activities.

Key words: Aryl amidoximyl chrysanthemumate, 1,2,4-Oxadiazole, Cyclization reaction, Biological activity

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JIN Gui-Yu, ZHAO Guo-Feng, ZHENG Jian-Yu. Studies on the Synthesis and Biological Activities of Aryl Amidoximyl Chrysanthemumates and 1,2,4-Oxadiazole Derivatives[J]. Chem. J. Chinese Universities, 1994, 15(7): 1009.

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Studies on the Synthesis and Biological Activities of Aryl Amidoximyl Chrysanthemumates and 1,2,4-Oxadiazole Derivatives

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