Isomerization/Chlorination of S-Alkyl(Aryl)O,O-dialkyl Dithiophosphate ——A New Method for Synthesis of S-Alkyl S-Alkyl(Aryl) Dithiophosphoric Acid Derivatives

Abstract

Abstract: Eleven compounds, among which nine are new compounds, of S-alkyl S-alkyl (aryl) dithiophosphpric acid derivatives have been synthesized by using a new convenient method which is based on the isomerization/chlorination of S-alkyl (aryl) O,O-dialkyl dithiophosphate with phosphorus oxychloride to give S-alkyl S-alkyl (aryl) phosphorochloridodithiolate.Then, this phosphorochlo-ridodithiolate reacts with various nuclosphiles, such as alcohol, phenol, mercaptan, thiophenol, ammonia in the presence of acid-binding agent to obtain S-alkyl S-alkyl (aryl) dithiophosphoric acid derivatives, such as S-alkyl S-alkyl (aryl) O-alkyl(aryl) phosphorodithiolate, S-alkyl S,S-dialkyl (aryl) phosphorotrithiolate, S-alkyl S-alkyl (aryl) phosphoramidodithiolate.The results of the tests in biological activity show that these compounds prepared possess a certain insecticidal or fungicidal activ-itiy.

Key words: Phosphorodithiolate, Phosphorotrithiolate, Phosphoramidodithiolate, Chlorination, Iso-merization

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TANG Chu-Chi, WU Gui-Ping . Isomerization/Chlorination of S-Alkyl(Aryl)O,O-dialkyl Dithiophosphate ——A New Method for Synthesis of S-Alkyl S-Alkyl(Aryl) Dithiophosphoric Acid Derivatives[J]. Chem. J. Chinese Universities, 1993, 14(5): 642.

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Isomerization/Chlorination of S-Alkyl(Aryl)O,O-dialkyl Dithiophosphate ——A New Method for Synthesis of S-Alkyl S-Alkyl(Aryl) Dithiophosphoric Acid Derivatives

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