高等学校化学学报

高等学校化学学报 ›› 2000, Vol. 21 ›› Issue (S1): 431.

• Synthetic Sciences • 上一篇    下一篇

Planar Chiral Ligands:Design and Applications in Asymmetric Synthesis

HOU Xue-Long, DENG Wei-Ping, YOU Shu-Li, WU Xun-Wei, DAI Li-Xi   

  1. Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
  • 出版日期:2000-12-31 发布日期:2000-12-31
  • 基金资助:

    Financial supported by National Natural Science Foundation of China.

Planar Chiral Ligands:Design and Applications in Asymmetric Synthesis

HOU Xue-Long, DENG Wei-Ping, YOU Shu-Li, WU Xun-Wei, DAI Li-Xi   

  1. Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
  • Online:2000-12-31 Published:2000-12-31
  • Supported by:

    Financial supported by National Natural Science Foundation of China.

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摘要：

Chiral ligands play an important role in asymmetric synthesis. Among them the ligands having planar chirality attract more interesting of organic chemists because of their unique structure. Recently, some new types of planar chiral ligands, including 1,1'-disubstituted ferrocene 1, bis(ferrocene carboxylic)diaminocyclohexane 2, and benzylic substituted cyclophane 3, are synthesized (Scheme 1)[1]. These chiral ligands have been successfully used in asymmetric allylic alkylation, Heck reaction, etc. The role of planar chirality in asymmetric induction by using NMR and X-ray are also studied.

Abstract:

Chiral ligands play an important role in asymmetric synthesis. Among them the ligands having planar chirality attract more interesting of organic chemists because of their unique structure. Recently, some new types of planar chiral ligands, including 1,1'-disubstituted ferrocene 1, bis(ferrocene carboxylic)diaminocyclohexane 2, and benzylic substituted cyclophane 3, are synthesized (Scheme 1)[1]. These chiral ligands have been successfully used in asymmetric allylic alkylation, Heck reaction, etc. The role of planar chirality in asymmetric induction by using NMR and X-ray are also studied.

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