高等学校化学学报

高等学校化学学报

• 研究简报 • 上一篇    下一篇

川麦冬中的新呋甾皂苷的分离与鉴定

徐暾海1, 陈萍2, 徐雅娟2, 郝羚竹2, 解生旭2, 徐东铭2   

    1. 北京中医药大学中药学院, 北京 100102;
    2. 吉林省中医中药研究院, 长春 130021
  • 收稿日期:2006-03-06 修回日期:1900-01-01 出版日期:2007-02-10 发布日期:2007-02-10
  • 通讯作者: 徐雅娟

Separation and Identification of New Furosteroidal Saponin from Ophiopogon japonicus(Thunb.) Ker-Gawl

XU Tun-Hai1, CHEN Ping2, XU Ya-Juan2, HAO Ling-Zhu2, XIE Sheng-Xu2, XU Dong-Ming2   

    1. College of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100102, China;
    2. Academy of Traditional Chinese Medicine and Material Medica of Jilin Province, Changchun 130021, China
  • Received:2006-03-06 Revised:1900-01-01 Online:2007-02-10 Published:2007-02-10
  • Contact: XU Ya-Juan

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被引次数

16

摘要： 从川麦冬块根总皂苷中分离并鉴定了4个双糖链甾体皂苷化合物, 其中化合物1为新化合物, 化合物2~4是已知化合物.

关键词: 川麦冬, 甾体皂苷, 麦冬呋甾皂苷A

Abstract: Traditional Chinese Medicine “maidong”[Ophiopogon japonicus(Thunb.) Ker-Gawl] is the important medicine used to treat cardiovascular diseases. A new furosteroidal saponin, together with three known steroidal saponins, was isolated from the tuber of Ophiopogon japonicus(Thunb.) Ker-Gawl. The structure of the new furosteroidal saponin, named Ophiopogoside A, was elucidated as 26-O-β-D-glucopyranosyl-(25S)-1β,3β,22α,26-tetrahydroxyfurot-5-ene 3-O-[-α-L-arabinopyranosyl(1→3)]-α-L-rhamnopyranosyl(1→2)-β-D-fucopyranoside mainly by using 1D, 2D NMR techniques, ESI-MS analysis as well as chemical methods.

Key words: Ophiopogon japonicus, Steroidal saponin, Ophiopogoside A

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