高等学校化学学报

高等学校化学学报

• 研究简报 • 上一篇    下一篇

五叶木通中一个新的三萜成分

刘桂艳1, 马双成2, 郑健2, 余振喜2, 林瑞超2   

    1. 北京理工大学生命科学与技术学院, 北京 100081;
    2. 中国药品生物制品检定所, 北京 100050
  • 收稿日期:2005-10-24 修回日期:1900-01-01 出版日期:2006-11-10 发布日期:2006-11-10
  • 通讯作者: 林瑞超

A New Triterpene from Akebia Quinata Stem

LIU Gui-Yan1, MA Shuang-Cheng2, ZHENG Jian2, YU Zhen-Xi2, LIN Rui-Chao2   

    1. School of Life Science & Technology, Beijing Institute of Technology, Beijing 100081, China;
    2. National Institute for the Control of Pharmaceutical & Biological Products, Beijing 100050, China
  • Received:2005-10-24 Revised:1900-01-01 Online:2006-11-10 Published:2006-11-10
  • Contact: LIN Rui-Chao

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被引次数

19

摘要： 对五叶木通藤茎进行了较为系统的研究, 从其体积分数为80%的乙醇提取物的正丁醇部分分离得到3个三萜成分, 通过理化性质和波谱分析鉴定为: 3α,24-二羟基-30-去甲齐墩果烷-12,20(29)-双
烯-28-酸(Ⅰ); 3α,24,29-三羟基齐墩果烷-12-烯-28-酸(Ⅱ); 2α,3β,23-三羟基齐墩果烷-12-烯-28-酸(Ⅲ). 其中化合物Ⅱ为新化合物, 命名为木通茎酸(Quinatic stem acid).

关键词: 木通属, 五叶木通, 三萜, 木通茎酸

Abstract: To study the chemical constituents, the ethanol extract of dried stem of Akebia quinata(Thunb.) Decne. was seperated by dichloromethane, n-butanol in sequence. The n-butanol extract was further isolated by D101 macroporous resin and silica gel column chromatography. A new triterpene with two known triterpenes were isolated, their structures were identified as 3α,24-dihydroxy-30-norolean-12,20(29)-dien-28-oic acid (Ⅰ), 3α,24,29-trihydroxyolean-12-en-28-oic acid (Ⅱ), 2α,3β,23-trihydroxyolean-12-en-28-oic acid (Ⅲ). The new compound Ⅱ was nominated as quinatic stem acid. The structures were identified and elucidated by physicochemical properties and spectral analysis.

Key words: Akebia, Akebia quinata(Thunb.)Decne., Triterpene, Quinatic stem acid

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