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PMMA人工晶状体表面的CF4/O2等离子体修饰

张丽华1, 吴迪1, 陈亚芍1, 李雪娇1, 赵宝明1, 黄长征2   

    1. 应用表面与胶体化学教育部重点实验室, 陕西师范大学化学与材料科学学院, 西安 710062;
    2. 爱邦眼科器械有限责任公司, 郑州 450008
  • 收稿日期:2008-01-23 修回日期:1900-01-01 出版日期:2008-09-10 发布日期:2008-09-10
  • 通讯作者: 陈亚芍

Surface Modification of PMMA IOL by CF4/O2 RF-plasma

ZHANG Li-Hua1, WU Di1, CHEN Ya-Shao1*, LI Xue-Jiao1, ZHAO Bao-Ming1, HUANG Chang-Zheng2   

    1. Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Materials Science, Shaanxi Normal University, Xi’an 710062, China;
    2. Able Eye Device Co. Ltd., Zhengzhou 450008, China
  • Received:2008-01-23 Revised:1900-01-01 Online:2008-09-10 Published:2008-09-10
  • Contact: CHEN Ya-Shao

摘要: 为了改善聚甲基丙烯酸甲酯(PMMA)人工晶状体的生物相容性和透光性, 采用CF4/O2等离子体技术修饰其表面. 通过衰减全反射红外光谱(ATR-FTIR)、X射线光电子能谱(XPS)、静态接触角(CA)测定、扫描电子显微镜(SEM)、紫外-可见近红外光谱(UV-Vis)等方法进行表征, 结果表明, 经CF4/O2等离子体处理后, PMMA表面的含氟和含氧基团增加, 其表面的亲水性增强, 生物相容性改善, 紫外光的隔离效率增大. 因此, 通过CF4/O2等离子体修饰能够有效地改善PMMA人工晶状体的性质.

关键词: PMMA人工晶状体, CF4/O2, 等离子体处理, 生物相容性, 透光性

Abstract: To improve biocompatibility and transmittance of polymethyl methacrylate intraocular lens(PMMA IOL), the surface of PMMA IOL was treated by CF4/O2 redio-frequency(RF)-plasma. The modified PMMA IOLs were characterized by the attenuated total reflectance Fourier transfer infrared spectroscopy(ATR-FTIR), X-ray photoelectron spectroscopy(XPS), the contact angle(CA) measurement, scanning electron microscopy(SEM) and ultraviolet-visible spectroscopy(UV-Vis), respectively. The results indicated that the treatment of CF4/O2 RF-plasma could make the modified PMMA IOL not only increase the contents of fluorine and oxygen, hydrophilicity and anti-ultroviolet radiation but also improve biocompatibility. Based on these results, the treatment of CF4/O2 RF-plasma is an effective method to improve the performance of PMMA IOL.

Key words: PMMA IOL, CF4/O2, Plasma treatment, Biocompatibility, Transmittance

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