CJCU

Chem. J. Chinese Universities ›› 1997, Vol. 18 ›› Issue (8): 1321.

• Articles • Previous Articles     Next Articles

Hydrolytic Metalloenzyme Activity of Zinc(Ⅱ) Complex of Tris (2-benzimidazylmethyl) amine

CHEN Wan-Dong1, ZHU Shou-Rong1, LIN Hua-Kuan1, LIN Chun-Chen2, LIN Mei-Rong2, CHEN Rong-Ti1   

  1. 1. Department of Chemistry, Nankai University, Tianjin 300071;
    2. Moden OPtics Institute, Nankai University, Tianjin 300071
  • Received:1996-08-09 Online:1997-08-24 Published:1997-08-24

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Abstract: The hydrolytic kinetics of p-nitrophenol acetate(NA) catalyzed by zinc(II) com-plex of Tris (2-benzimidazylmethyl)amine (NTB) has been studied. It was shown that the catalytic hydrolytic rate is of first-order to both zinc(II) complex and NAconcentrations.The second-order rate constant is kcat=0.12mol-1·L·s-1 (T=298K, I=0.10mol/L KNO3,0.02mol/L Tris buffer, 40% CH3CNaqueous solution).This is one of the most efficient hydrolytic metalloenzyme model compounds reported up to now. The increase of CH3CNcontents in the solution greatly decreased the hydrolytic activity of the nucleophiles.

Key words: Hydrolytic metalloenzyme, Zinc complex, Tripod ligand, 2-Benzoimidazole

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