Application of 2-(1,3-Dithian-2-ylidene)-3-oxobutanoic Acid as 1,3-Propanedithiol Equivalent in Thioacetalization Reactions

Chem. J. Chinese Universities ›› 2005, Vol. 26 ›› Issue (12): 2237.

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Application of 2-(1,3-Dithian-2-ylidene)-3-oxobutanoic Acid as 1,3-Propanedithiol Equivalent in Thioacetalization Reactions

OU YANG Yan^1,2, YU Hai-Feng¹, DONG De-Wen¹, LIU Jun¹, WANG Mang¹, LIU Qun^1*

1. Faculty of Chemistry, Northeast Normal University, Changchun 130024, China;2. Department of Chemistry, Yili Normal College, Yining 835000, China

Received:2004-11-15 Online:1905-03-14 Published:1905-03-14
Contact: LIU Qun;E-mail:liuqun@nenu.edu.cn

Abstract

Abstract:

The thioacetalization of carbonyl compounds 2 by using 2-(1,3-dithian-2-ylidene)-3-oxobutanoic acid as 1,3-propanedithiol equivalent and ethanol as solvent was investigated. The results showed that the thioacetalization of various carbonyl compounds proceeded smoothly and rapidly and afforded the corresponding dithioacetals 3 in high yields. Moreover, the thioacetalization exhibited a high chemoselectivity between aldehyde and ketone.

Key words: 2-(1,3-Dithian-2-ylidene)-3-oxobutanoic acid; 1,3-Propanedithiol equivalent; Carbonyl compound; Thioacetalization; Chemoselectivity, 2-(1,3-Dithian-2-ylidene)-3-oxobutanoic acid, 1,3-Propanedithiol equivalent, Carbonyl compound, Thioacetalization, Chemoselectivity

CLC Number:

O621.3

TrendMD:

OU Yang-Yan, YU Hai-Feng, DONG De-Wen, LIU Jun, WANG Mang, LIU Qun. Application of 2-(1,3-Dithian-2-ylidene)-3-oxobutanoic Acid as 1,3-Propanedithiol Equivalent in Thioacetalization Reactions[J]. Chem. J. Chinese Universities, 2005, 26(12): 2237.

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Application of 2-(1,3-Dithian-2-ylidene)-3-oxobutanoic Acid as 1,3-Propanedithiol Equivalent in Thioacetalization Reactions

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