Chem. J. Chinese Universities ›› 2005, Vol. 26 ›› Issue (12): 2237.

• Articles • Previous Articles     Next Articles

Application of 2-(1,3-Dithian-2-ylidene)-3-oxobutanoic Acid as 1,3-Propanedithiol Equivalent in Thioacetalization Reactions

OUYANG Yan1,2, YU Hai-Feng1, DONG De-Wen1, LIU Jun1, WANG Mang1   

  1. 1. Faculty of Chemistry,Northeast Normal University,Changchun 130024,China;
    2. Department of Chemistry,Yili Normal College,Yining 835000,China
  • Received:2004-11-15 Online:2005-12-24 Published:2005-12-24

Abstract: The thioacetalization of carbonyl compounds 2 by using 2-(1,3-dithian-2-ylidene)-3-oxobutanoic acid as 1,3-propanedithiol equivalent and ethanol as solvent was investigated.The results showed that the thioacetalization of various carbonyl compounds proceeded smoothly and rapidly and afforded the corresponding dithioacetals 3 in high yields.Moreover,the thioacetalization exhibited a high chemoselectivity between aldehyde and ketone.

Key words: 2-(1,3-Dithian-2-ylidene)-3-oxobutanoic acid; 1,3-Propanedithiol equivalent; Carbonyl compound; Thioacetalization; Chemoselectivity, 2-(1,3-Dithian-2-ylidene)-3-oxobutanoic acid, 1,3-Propanedithiol equivalent, Carbonyl compound, Thioacetalization, Chemoselectivity

CLC Number: 

TrendMD: