Abstract: In an electrolytic cell with proton exchange membrane as the diaphragm, the electrooxidation conditions of 2-picoline at a PbO₂ electrode were studied by using cyclic voltammetry, linear scan voltammetry and potentiostatic electrolysis in acetone/H₂O, acetonitrile/H₂O and 2-butanone/H₂O mixed solvents respectively, and after comparison of the selectivity, the current efficiency and the current density, it was found that in acetone/water mixed solvents the selectivity and the current efficiency of electrooxidation from 2-picoline to 2-pyridinecarboxylic acid were the highest , the current density of anode oxidation was also obviously increased. The electrooxidation from 2-picoline to 2-pyridinecarboxylic acid in acetone/water mixed solvents can completely replace to that in pure water.

Key words: 2-Picoline, 2-Pyridinecarboxylic acid, Organic compound/water mixed solvent, Elctrooxidation